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ENCYCLOPEDIA OF EARTH AND ATMOSPHERIC SCIENCES ENCYCLOPEDIA OF MATHEMATICAL SCIENCES ENCYCLOPEDIA OF BIOLOGICAL,PHYSIOLOGICAL AND HEALTH SCIENCES ENCYCLOPEDIA OF SOCIAL SCIENCES AND HUMANITIES ENCYCLOPEDIA OF PHYSICAL SCIENCES,ENGINEERING AND TECHNOLOGY RESOURCES ENCYCLOPEDIA OF CHEMICAL SCIENCES,ENGINEERING AND TECHNOLOGY RESOURCES ENCYCLOPEDIA OF WATER SCIENCES,ENGINEERING AND TECHNOLOGY RESOURCES ENCYCLOPEDIA OF ENERGY SCIENCES,ENGINEERING AND TECHNOLOGY RESOURCES ENCYCLOPEDIA OF ENVIRONMENTAL AND ECOLOGICAL SCIENCES,ENGINEERING AND TECHNOLOGY RESOURCES ENCYCLOPEDIA OF FOOD AND AGRICULTURAL SCIENCES,ENGINEERING AND TECHNOLOGY RESOURCES ENCYCLOPEDIA OF HUMAN RESOURCES POLICY AND MANAGEMENT ENCYCLOPEDIA OF NATURAL RESOURCES POLICY AND MANAGEMENT ENCYCLOPEDIA OF DEVELOPMENT AND ECONOMIC RESOURCES ENCYCLOPEDIA OF INSTITUTIONAL AND INFRASTRUCTURAL RESOURCES ENCYCLOPEDIA OF TECHNOLOGY,INFORMATION, AND SYSTEMS MANAGEMENT RESOURCES ENCYCLOPEDIA OF REGIONAL SUSTAINABLE DEVELOPMENT REVIEWS

The above simplified figure illuminates the essential interconnectedness of the sixteen component encyclopedias of EOLSS.

 In the real world, the various knowledge domains do not exist in isolation from each other. They form an integrated whole, with links in all directions. It is well known that all forms of human knowledge are inter-connected and inter-related. EOLSS mimics this complexity, the automatic inter-connectedness of the various subject categories facilitating navigation through the vast landscape of EOLSS knowledge. This provides the user with an effective and efficient tool to search, navigate and browse through each of the component encyclopedias, through any combination of the sixteen, or through the whole of EOLSS.

ENCYCLOPEDIA OF BIOLOGICAL, PHYSIOLOGICAL AND HEALTH SCIENCES

CONTENT OUTLINE (partial listing)

 

BIOLOGICAL SCIENCE FOUNDATIONS

    The Beginning of Modern Biological Science

        What Is Biological Life?

        Microscopic Life

        The Origin of Life

        Evolution and the Origin of Species

    Genetics and Evolution

        Genetics in the Modern World

        The Mechanisms Involved in Evolution

        Humanity, the Environment, and Evolution

        Artificial Evolution

    The Molecular Basis of Life

        The Cell

        The Gene

        The Biochemical Processes of Life

        Genetic Manipulation

    The Molecular Tree of Life

        Morphological Methods of Classifying Species

        Biochemical Methods of Classifying Species

        Gene-Based Classification

        Life On Earth Over the Last 4 Billion Years

    The Limits of Life on Earth

        Water as a Limiting Factor

        Ionic Concentration as a Limiting Factor

        Temperature as a Limiting Factor

        Acidity/Alkalinity as a Limiting Factor

        Gaseous Atmosphere as a Limiting Factor

        Energy as a Limiting Factor

        The Edges of the Envelope

    Life Elsewhere in the Universe

        Is Carbon-Based Life Alone?

        Carbon-Based Life on the Planets

        Carbon-Based Life in Other Star Systems

        Panspermia

 

ORGANIC CHEMICALS INVOLVED IN LIFE PROCESSES

    Proteins

        Amino Acids

        Polypeptide chains

        Primary structure

        Secondary structure

        Tertiary structure

        Quaternary structure

        Enzymes

    Carbohydrates

        Monosaccarides

            Stereo-isomerization

            Cyclic Structures

        Disaccharides

    Polysaccharides

    Lipids

        Fatty acids

        Fatty acids in humans

        Triacyglycerols

        Phospholipids

        Steroids

    Nucleic Acids

        Nucleotides

        The nucleic acids

            DNA

            DNA can have different structural features

            RNA

 

CARBON FIXATION

Carbon fixation in higher plants

The Light Dependent Reactions of Plant Photosynthesis

The Light Independent Reactions of Photosynthesis: Synthesis of Carbohydrates

C3, C4 and CAM metabolism

Algae

Bacteria

Purple Bacteria

Green Sulfur Bacteria

Green Gliding Bacteria

Heliobacteria

Global photosynthesis and the atmosphere

 

EUKARYOTE CELL BIOLOGY

    Origin of Eukaryotes

    Cellular differentiation in multicellular organisms

        Plants

        Animals

    Eukaryotic cell structure

    Organization of eukaryotic cells

        Plasma membrane

        Extracellular matrices

        Proteins synthesis and transport

        Cytoskeleton and movement

        Nucleus

            Genomes

            Gene expression

            Maintaining the genome

        Organelles

    The cell cycle

        Mitosis

        Meiosis

    Regulation of cell growth

        Signal transduction

        Programmed cell death

        Cancer

    Experimental models

        Yeast

        Arabidopsis

        Drosophila

        The mouse

        Cell culture

        Separation of cellular contents

        Tracing biochemical pathways

    Future Investigations

 

CELL THEORY, PROPERTIES OF CELLS AND THEIR DIVERSITY

    The Composition of Life

        Origin of organic molecules

        RNA and the origin of life

    Cell as the unit of life

        Cell theory

        The theory of organisms

        Cell size

    The diversity of life

        Origin of the first cell

        The endosymbiont hypothesis

    Cellular diversity

        Plant tissue diversity

            Dermal tissue

            Vascular tissue

            Ground tissue

        Animal tissue diversity

            Epithelial tissue

            Muscle tissue

                Connective tissue

                Nervous tissue

                Blood

                Sensory cells

                Germ cells

    Tissue maintenance and renewal

        Tissue renewal rates

        Stem cells

    Discussion

 

CELL MORPHOLOGY AND ORGANIZATION

    The cytoplasm

    Membranes

        Structure

        The cell cortex

        Transmembrane proteins

        Endoplasmic reticulum

        Golgi apparatus

        Lysosomes

    Extracellular matrices

        Glycocalyx

        Cell walls

    Cytoskeleton

        Microfilaments or Actin filaments

        Intermediate filaments

        Microtubules

    Cilia and Flagella

    Connections between cells

         Plasmodesmata

         Desmosomes

         Tight junctions

         Gap junctions

    Vacuoles

        Central vacuoles

        Contractile vacuoles

    Cell organization

    Membrane transport systems

        Passive transport

        Active transport

        Endocytosis

    Protein synthesis

        Initiation

        Elongation

        Termination

    Protein targeting

        Proteins made in the cytoplasm

        Chaperones

        Proteins made on the rough endoplasmic reticulum

        The Golgi apparatus

        Vesicles

    Protein breakdown

        Proteosomes

        Lysosomes

    Cell movement

        Microfilaments and cell movement

        Myosin

        Microtubules

        Cilia and flagella movement

 

CELL NUCLEUS AND CHROMATIN STRUCTURE

    The nucleus

        The nuclear membrane

        The nuclear pore

            Structure of the nuclear pore

            Function of the nuclear pore

        The lamina

    The genome

    Chromosomes

        The nucleosome

            Histones

            DNA condensation

        Functional domains

            Centromere

            Telomere

    DNA replication

        Origin of replication

        DNA polymerases

        Nucleosome replication

    Nucleolus

        rRNA genes and expression

        Ribosome assembly and export

    Transcription

        RNA polymerases

        Eukaryote promotors

        Initiation of transcription

        RNA elongation

        Termination of transcription

        Regulation of transcription

        Chromatin structure and transcription

    mRNA processing and turnover

        Capping

        Polyadenylation

        Splicing

        RNA editing

    tRNA processing and turnover

 

ORGANELLES AND OTHER STRUCTURES IN CELL BIOLOGY

The distribution and function of the mitochondrion

The structure of the mitochondrion

The mitochondrial genome

The mitochondrial genetic code and translation mechanism

Maternal inheritance of the mitochondrion

Distribution and structure of the chloroplast

The chloroplast genome

The chloroplast genetic code

Maternal inheritance of the chloroplast

An endosymbiotic origin for the mitochondrion and chloroplast

Evolution of the mitochondrion

Evolution of the Chloroplast

Other possibly endosymbiotic organelles

 

MITOSIS, CYTOKINESIS, MEIOSIS AND APOPTOSIS

    The eukaryote cell cycle

        Phases

    Mitosis

        Prophase

        Metaphase

        Anaphase

        Telophase

        Cytokinesis

    Meiosis

        Stages of meiosis

    Fertilization and development

    Regulators of Cell cycle

        Checkpoints

            G1/S checkpoint

            G2/M checkpoint

        Mitosis checkpoint

        Maturation promoting factor

        Cyclin dependent protein kinases

            Diversity and action

            Regulation

            Cyclin regulation of mitosis

        Growth factors

        Inhibitors of cell cycle progression

    Programmed cell death

        Triggers of apoptosis

        Pathways leading to apoptosis

 

CELL GROWTH REGULATION, TRANSFORMATION AND METASTASES

    Signal molecules

        Transmembrane signals for large signal molecules

        Small signal molecules

    Switches of intracellular molecules

        Regulation of signal molecules

    Cell surface receptors

         Ion-channel-linked receptors

        G-protein-linked receptors

            General structure and function of G-protein-receptors.

            G-proteins and ion-channels

            G-proteins and enzymes.

        Enzyme-linked receptors

            Protein tyrosine kinases

            Signaling domains SH2 and SH3.

            Ras/MAPK pathway

        The JAK/STAT pathway

    Cancer

        Ras proto-oncogenesis

        Signal transduction

        Kinases

        Insertions, deletions and translocations

        Viral oncogenesis

            DNA viruses

            RNA viruses

        Tumor suppressor genes

 

MICROBIOLOGY

Taxonomy

Morphology

Eucaryote Microorganisms - Protozoa