Biotechnology

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Editor(s):
Horst W. Doelle, Stefan Rokem, Marin Berovic
Volume(s):
15
Published:
2009
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This Encyclopedia of Biotechnology is a component of the global Encyclopedia of Life Support Systems (EOLSS), which is an integrated compendium of twenty one Encyclopedias.

Biotechnology draws on the pure biological sciences (genetics, animal cell culture, molecular biology, microbiology, biochemistry, embryology, cell biology) and in many instances is also dependent on knowledge and methods from outside the sphere of biology (chemical engineering, bioprocess engineering, information technology, biorobotics).

This 15-volume set contains several chapters, each of size 5000-30000 words, with perspectives, applications and extensive illustrations. It carries state-of-the-art knowledge in the field and is aimed, by virtue of the several applications, at the following five major target audiences: University and College Students, Educators, Professional Practitioners, Research Personnel and Policy Analysts, Managers, and Decision Makers and NGOs

Horst W. Doelle was born in 1932 and studied biology at the University of Jena, Germany (1950–4). He studied for his doctorate at the University of Göttingen, Germany (1955–7) in antibiotic production. After receiving his doctorate, he worked in the wine and brewing industry in Germany before taking up an appointment with CSIRO in Australia in 1960. After four years’ wine research, he took up the challenge to build up microbial physiology and fermentation technology at the Department of Microbiology, the University of Queensland, Brisbane, Australia. He received his D.Sc. in 1976 and his D.Sc. honoris causain 1998. He has participated in and conducted numerous training courses in developing countries. Aftertwenty-nine years’ teaching he retired in 1992. His research area was regulation of anaerobic/aerobic metabolism, microbial technology (Zymomonas ethanol technology), and socio-economic biotechnology using micro-organisms for waste management.

J. Stefan Rokem is a Senior Lecturer at the Department of Molecular Genetics and Biotechnology at the Hebrew University of Jerusalem, Israel. He earned his M.Sc. in Microbial Biochemistry and Fermentation Technology from the Imperial College of Science and Technology at the University of London, United Kingdom. He completed his Ph.D. studies in Applied Microbiology at the Hebrew University of Jerusalem, Israel with a thesis on “Production of Single Cell Protein”. In addition to his teaching duties at the Hebrew University, Dr. Rokem serves as a scientific consultant to local biotechnology companies and is a reviewer of several journals and granting agencies. He has been on the executive committee of the International Organization of Biotechnology and Bioengineering for several years, serving as one of the representatives of the Middle East. Dr. Rokem has given several guest lectures and courses in Bioengineering and the use of Biotechnology for the improvement of the Environment in South and Central America. Recently Dr. Rokem developed a novel curriculum in Biotechnology for the Open University of Israel. During his academic career he has co-authored over 60 peer reviewed papers, written several book chapters, co edited one book and written a monograph on the use of Biotechnology to Improve the Environment. The main research interests of Dr. Rokem are the regulation of antibiotic production in Actinobacteria, production of organic acids with filamentous fungi and the use of Biotechnology to reach Sustainable Development, mainly novel methods for sewage treatment. He has spent sabbaticals at Yale University, New Haven, CT, USA; Royal Institute of Technology, Stockholm, Sweden; MIT, Cambridge, MA, USA and The Danish Technical University, Copenhagen, Denmark.

Marin Berovic was born on 22.3.1951 in Novo mesto, Slovenia. He obtained in 1976 his B.Sc., 1979 M.Sc and 1974 Ph.D in Chemical and Biochemical Engineering, on Faculty of Chemistry and Chemical Engineering, University of Ljubljana. In 1984 he received degree of M.A., Master of Art, on Academy of Beautiful Arts, Dept.Restavration and conservation of Art monuments, of University of Ljubljana. From 1976 to 1998 he was as a higher research scientist and a head of bioreactor engineering laboratory on National Institute of Chemistry involved in research in thirty five research project mostly as a head of research. He did his scientific training on bioprocess engineering on Institut für Biochemische Technologie und Microbiologie, Technische Universitat Graz,Austria and on Institut fur Technische Chemie Technische Universitat Hannover, Germany, modelling in biotechnology on Technical University Delft-Leiden,The Netherlands and Technical University of Denmark, Lyngby, Denmark and research in rheology of filamentous fungal broths on University of Strathclyde, Glasgow, Great Britain. In 1996 he was elected as assistant professor of bioprocess engineering on Biotechnical Faculty and in 1996 as assistant professor of art technology on Academy of Beautiful Arts, University of Ljubljana. From 2002 he continued as associated professor of biotechnology on Faculty of Chemistry and Chemical Engineering, Dept.Chemical, Biochemical and Ecology Engineering University of Ljubljana, where he is full time professor on biotechnology and biochemical engineering. From 1986 he is started as the representative of Yugoslavia and from 1991 Slovenia in European Federation on Biotechnology (EFB). In 1989 he established EFB Bioreactor Engineering Course, doctoral/post doctoral engineering course the principal Master Course in biochemical engineering that he is managing still in the present time. From 2002 he is vice-chairman of International Organization on Biotechnology and Bioengineering. He is a Member of New York Academy of Sciences, Member of Executive Board of European Federation on Biotechnology and Chairman of European Section on Biochemical Engineering Sciences. He is Editor of biochemical engineering in New Biotechnology, Associated Editor of Biotechnology Annual Review, he edited 8 books on biochemical engineering and he obtained three National awards on research and innovations

Table of Contents (151 Chapters)
  • 1. Biotechnology

    Horst W. Doelle,Edgar J. DaSilva
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    Volume : 1
  • 2. Fundamentals in Biotechnology

    H. W. Doelle,E. J. DaSilva
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    Price : US$7.50
    Volume : 1
  • 3. Microbial Cell Culture

    Horst W. Doelle
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    Price : US$15.00
    Volume : 1
  • 4. Algal Cell Culture

    Peter A. Thompson
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    Volume : 1
  • 5. Plant Cell Culture

    Mary Taylor
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    Volume : 1
  • 6. Mammalian Cell Culture

    C.P. Marquis,
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    Volume : 1
  • 7. Cell Thermodynamics and Energy Metabolism

    Horst W. Doelle
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    Volume : 1
  • 8. Basic Strategies of Cell Metabolism

    Horst W. Doelle
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    Volume : 1
  • 9. The Importance of Microbial Culture Collections and Gene Banks in Biotechnology

    Lourdes M. Mahilum-Tapay
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    Volume : 1
  • 10. Biosafety in Biotechnology

    Jean-Marc Collard, Didier Breyer, Suzy Renckens, Myriam Sneyers, Ellen Van Haver, Bernadette Van Vaerenbergh, and William Moens
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    Volume : 1
  • 11. Bioinformatics

    Bojana Boh
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    Volume : 1
  • 12. Microbial Chemistry

    Horst W. Doelle and Monica Wilkinson
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    Volume : 1
  • 13. A Concise History Of Biotechnology – Some Key Determinants

    John E. Smith
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    Volume : 1
  • 14. Methods in Biotechnology

    David A. Mitchell,Adriana Contin
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    Volume : 2
  • 15. Instrumentation and Control of Bioprocesses

    Ricardo Pérez-Correa and Eduardo Agosin
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    Volume : 2
  • 16. Chemical Methods Applied to Biotechnology

    Nadia Krieger and Luiz P. Ramos,José D. Fontana
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    Volume : 2
  • 17. Physical Methods Applied to Biotechnology

    José D. Fontana,Nádia Krieger and Luiz P. Ramos
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    Volume : 2
  • 18. Mathematical Modeling in Biotechnology

    Joan Mata-Alvarez,David A. Mitchell
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    Volume : 2
  • 19. Biosensors

    E. Galindo
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    Volume : 2
  • 20. Molecular Biotechnology : Application in Livestock System

    Ala E. Lew-Tabor
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    Volume : 2
  • 21. Methods in Gene Engineering

    Chanan Angsuthanasombat
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    Volume : 3
  • 22. Genetic Manipulation of Bacteria

    Christopher M Thomas
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    Volume : 3
  • 23. Genetic Engineering Of Fungal Cells

    Margo M. Moore
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    Volume : 3
  • 24. Genetic Engineering of Algal Species

    Ann-Sofi Rehnstam-Holm,Anna Godhe
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    Volume : 3
  • 25. Genetic Engineering of Plants

    J. A. Thomson
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    Volume : 3
  • 26. Genetic Engineering of Mammalian Cells

    Hugo H. Montaldo
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    Volume : 3
  • 27. Protein Engineering

    D. N. Rubingh and R. A. Grayling
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    Volume : 3
  • 28. Health and Gene Sciences

    Yongyuth Yuthavong
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    Volume : 3
  • 29. GMO - Technology and Malnutrition - Public Sector Responsibility and Failure

    Ingo Potrykus
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    Volume : 3
  • 30. New opportunities revealed by biotechnological Exploration of Extremophiles

    Mircea Podar and Anna-Louise Reysenbach
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    Volume : 3
  • 31. The Challenges of Genetic Information

    Trudo Lemmens and Lisa Austin
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    Volume : 3
  • 32. Principles of Metabolic Engineering

    John Villadsen
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    Volume : 3
  • 33. Bioprocess Engineering - Bioprocess Analysis through Calorimetry and Biothermodynamics

    Thomas Maskow,Richard B. Kemp
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    Volume : 4
  • 34. Bioreactors

    Marin Berovic
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    Volume : 4
  • 35. Upstream Processing - Sterilization in Bioprocess Technology

    Marin Berovic
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    Volume : 4
  • 36. Downstream Processing of Proteins Using Foam Fractionation

    Cesar C. Santana,Liping Du and Robert D. Tanner
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    Volume : 4
  • 37. Process Optimization Strategies for Biotechnology Products: From Discovery to Production

    M. J. Kennedy, S. L. Reader, D. Krouse, and S. Hinkley
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    Volume : 4
  • 38. Microbial Dynamic Transformation

    J.M. Bruno-Bárcena,E. Picó-Marco and J.L. Navarro,J. Picó
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    Volume : 4
  • 39. Biotransformations

    Hiltrud Lenke,Andreas Schmid
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    Volume : 4
  • 40. Biopesticide Production

    Nasrine Moazami
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    Volume : 6
  • 41. Secondary Products from Plant Tissue Cultures

    James C. Linden
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    Volume : 6
  • 42. Industrial Mycology

    J.S. Rokem
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    Volume : 6
  • 43. Biobutanol

    D. T. Jones
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    Volume : 6
  • 44. The Industrial Use of Enzymes

    Michele Vitolo
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    Volume : 6
  • 45. Production of Heterologous Hydrolysis Enzymes within Crop Biomass for Biofuel Ethanol

    Callista B. Ransom and Mariam B. Sticklen
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    Volume : 6
  • 46. Special Processes For Products, Fuel and Energy

    John A. Buswell
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    Volume : 7
  • 47. Bio-Refineries-Concept for Sustainability and Human Development

    Horst W. Doelle,Edgar J. DaSilva
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    Volume : 7
  • 48. Nutriceuticals from Mushrooms

    S.T. Chang,J. A. Buswell
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    Volume : 7
  • 49. Mushroom Production

    S. T. Chang
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    Volume : 7
  • 50. Pharmaceuticals from Algae

    Michael A. Borowitzka
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    Volume : 7
  • 51. Biodiesel

    Ariel Louwrier
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    Volume : 7
  • 52. Natural Food Colorants

    Philippe J. Blanc
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    Volume : 7
  • 53. Production of Alcohol for Fuel and Organic Solvent

    M. Bekers and A. Vigants
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    Volume : 7
  • 54. Biotechnological Applications of Acetic Acid Bacteria in Food Production

    Peter Raspor and Dušan Goranovič
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    Volume : 7
  • 55. A carbon-negative model for production of feed and fuel from biomass

    Thomas R Preston
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    Volume : 7
  • 56. Integrated Thermo-Biorefinery

    Michael Theroux
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    Volume : 7
  • 57. The Next Generation of Biofuels - A New Approach to the Production of Biofuels

    S. Mayfield Pierce
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    Volume : 7
  • 58. Plant Genome Mapping: Strategies And Applications

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    Volume : 7
  • 59. Biomass Feedstocks

    Ayhan Demirbas
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    Volume : 7
  • 60. Suggestions For Improving Cellulosic Biomass Refining

    H. R. Bungay
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    Volume : 7
  • 61. Biohydrogen - The Microbiological Production Of Hydrogen Fuel

    P. C. Hallenbeck,J. R. Benemann
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    Volume : 7
  • 62. Agricultural Biotechnology

    Nancy K. Karanja,James H. P. Kahindi
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    Volume : 8
  • 63. Fermented Foods and Their Processing

    Nduka Okafor
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    Volume : 8
  • 64. Essentials of Nitrogen Fixation Biotechnology

    James H. P. Kahindi,Nancy K. Karanja
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    Volume : 8
  • 65. Crop Protection through Pest-Resistant Genes

    Stanley Freeman,Anges W. Mwang’ombe
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    Volume : 8
  • 66. Composting Agricultural and Industrial Wastes

    G. J. Manderson
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    Volume : 8
  • 67. Silage for Animal Feed

    L. Mannetje
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    Volume : 8
  • 68. Transgenic Plants

    Kathleen L. Hefferon
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    Volume : 8
  • 69. Transgenic Technologies for Animals as Bioreactors

    Bin Wang,Xiangzhong (Jerry) Yang
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    Volume : 8
  • 70. Plant Breeding and Molecular Farming

    Philip A. Davies
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    Volume : 8
  • 71. Biotechnology and Agrobiodiversity

    Bert Visser,Jan-Peter Nap
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    Volume : 8
  • 72. The Economics of Agrobiotechnology

    J. Wesseler
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    Volume : 8
  • 73. Conventional Plant Breeding for Higher Yields and Pest Resistance

    Roberto García-Espinosa,Raoul A. Robinson
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    Volume : 8
  • 74. Transgenic Vegetable Crops For Managing Insect Pests and Fungal and Viral Diseases

    Zamir K. Punja
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    Volume : 8
  • 75. Farmers and Plant Genetic Resources

    Nadine Saad,Louise Sperling,Jacqueline A. Ashby
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    Volume : 8
  • 76. The Role Of Plant Genomics In Biotechnology

    A.Varma and N. Shrivastava
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    Volume : 8
  • 77. Role Of Plant Hormones In Legume Nodulation

    P. K. Chan and P.M. Gresshoff
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    Volume : 8
  • 78. Marine Biotechnology

    Karunasagar, Indrani
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    Volume : 9
  • 79. Molecular Aspects Of Steroid Action In Marine Fishes

    B.S. Nunez, S.L. Applebaum, A.H. Berg, G.E. Dressing, A.N. Evans and T.P. Barry
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    Volume : 9
  • 80. Marine Microbial Enzymes

    M. Chandrasekaran and S. Rajeev Kumar
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    Volume : 9
  • 81. Biotechnological tools in fish health Management

    Indrani Karunasagar
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    Volume : 9
  • 82. Molecular Tools for Improving Seafood Safety

    Karunasagar, Iddya
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    Volume : 9
  • 83. Marine Natural Products Biotechnology

    Russell T. Hill
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    Volume : 9
  • 84. Molecular Tools for the Study of Marine Microbial Diversity

    L.K. Medlin, K. Valentin, K. Metfies and K. Töbe,R. Groben
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    Volume : 9
  • 85. Bioremediation in the Marine Environment

    Karunasagar, Iddya
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    Volume : 9
  • 86. Biotechnology of Archaea

    Costanzo Bertoldo and Garabed Antranikian
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    Volume : 9
  • 87. Viable But NonCulturable Bacteria in the Marine Environment and the Biotechnological Tools to Detect Them

    Colwell, Rita R.
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    Volume : 9
  • 88. Extending Integrated Fish Farming Technologies To Mariculture In China

    Li Kangmin
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    Volume : 9
  • 89. Environmental Biotechnology - Socio-Economic Strategies for Sustainability

    Horst W.Doelle,Poonsuk Prasertsan
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    Volume : 10
  • 90. Recycling Livestock Excreta in Integrated Farming Systems

    T. R. Preston
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    Volume : 10
  • 91. Recycling of Agro-Industrial Wastes Through Cleaner Technology

    Poonsuk Prasertsan, Suteera Prasertsan and Aran H–Kittikun
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    Volume : 10
  • 92. Urban Rooftop Microfarms

    Geoff Wilson
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    Volume : 10
  • 93. Biomass and Organic Waste Conversion to Food, Feed, Fuel, Fertilizer, Energy and Commodity Products

    Horst W. Doelle
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    Volume : 10
  • 94. Health and Environmental Aspects of Recycled Water

    J.G. Atherton
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    Volume : 10
  • 95. Microorganisms as Catalysts for the Decontamination of Ecosystems and Detoxification of Organic Chemicals

    Wolfgang Babel and Roland H. Müller
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    Volume : 10
  • 96. Biohydrometallurgy

    F. Acevedo
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    Volume : 10
  • 97. Biodegradation of Xenobiotics

    S. Fetzner
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    Volume : 10
  • 98. Sustainable Aquaculture: Concept or Practice

    William A. Wurts
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    Volume : 10
  • 99. Biogas as Renewable Energy from Organic Waste

    Amrit B. Karki
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    Volume : 10
  • 100. Biodiversity: The Impact of Biotechnology

    Richard Braun,Klaus Ammann
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    Volume : 10
  • 101. Biotechnology in the Environment: Potential Effects on Biodiversity

    B.R. Johnson, and A.R. Hope
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    Volume : 10
  • 102. Bioremediation: an Overview

    M. Vidali
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    Volume : 10
  • 103. Microbial Resource Management: The Road to Go for Environmental Biotechnology

    W. Verstraete, L. Wittebolle, T. van de Wiele and N. Boon,K. Heylen, B. Vanparys and P. de Vos
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    Volume : 10
  • 104. Appropriate and Inappropriate Biotechnology for Developing Countries

    E.R. Orskov
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    Volume : 10
  • 105. Vermiculture Industry In Circular Economy

    Li Kangmin
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    Volume : 10
  • 106. Bio-Cultural Diversity and Medicine

    Edgar J. DaSilva,Murukesan V. Krishnapillai,Pier Giovanni d’Ayala
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    Volume : 11
  • 107. Blood: The Essence of Humanity

    Shilpa P. Mehta,Sunil J.Parekh,Edgar J. DaSilva
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    Volume : 11
  • 108. Compulsory License Regimes For Public Health In Europe

    Esther van Zimmeren and Geertrui Van Overwalle
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    Volume : 11
  • 109. Medical Mycology

    Stephen Davis
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    Volume : 11
  • 110. Lysine Biosynthesis In Bacteria- An Unchartered Pathway For Novel Antibiotic Design

    Con Dogovski, Sarah C. Atkinson, Sudhir R. Dommaraju, Renwick C. J. Dobson,Matthew A. Perugini,Lilian Hor,Craig A. Huton,Juliet A. Gerrard
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    Volume : 11
  • 111. Antibody Based Protein Research In Human Pathology

    C. Gulmann and C. Buckley,R. Cummins
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    Volume : 11
  • 112. Abzymes - A Challenge For The Medical Biotechnology And Public Health

    I. Getov,T. Argirova
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    Volume : 11
  • 113. The Role Of Phytobiotechnology In Public Health

    Kenneth Anchang Yongabi
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    Volume : 11
  • 114. Medical Biotechnology-Modern Development

    L.Y. Hsu,F.S. Teo,T.M. Chin
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    Volume : 11
  • 115. Bioinformatics on Post Genomic Era-> From Genomes to Systems Biology

    Vihinen,
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    Volume : 11
  • 116. Gene Therapy

    P. Lehtolainen,M.O. Laukkanen,S. Ylä-Herttuala
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    Volume : 11
  • 117. Tissue Engineering: Advances in Organ Replacement

    Lisa Riccalton-Banks, Andrew Lewis, and Kevin Shakesheff
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    Volume : 11
  • 118. The Nanostructure of the Nervous System and the Impact of Nanotechnology on Neuroscience

    Gabriel A.Silva
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    Volume : 11
  • 119. TP53 Gene and P53 Protein as Targets in Cancer Management and therapy

    Daniela Maurici and Pierre Hainaut
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    Price : US$15.00
    Volume : 12
  • 120. Plant-Made Vaccines- The Past, Present and Future

    A. M. Walmsley and D. D. Kirk
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    Volume : 12
  • 121. Transgenic Mice in Immunobiology

    Harri Alenius
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    Volume : 12
  • 122. Nanomedicine and Medical Nanorobotics

    Robert A. Freitas Jr.
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    Volume : 12
  • 123. Role of Xenobiotic Metabolism in Drug Discovery and Development

    Paivi Taavitsainen,Paavo Honkakoski,Risto Juvonen,Olavi Pelkonen,Hannu Raunio
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    Volume : 12
  • 124. From Gene to Clinical Product: An Overview of GMP Requirements Associated to the Development of New Biotherapeutics, in a Multiprocess/Multiproduct Facility

    Jean-François POLLET,Alex BOLLEN
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    Volume : 12
  • 125. The Impact of Patents on Medical Biotechnology

    D. Nicol and J. Nielsen
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    Volume : 12
  • 126. Biofilm of Medical Importance

    Morten Alhede,Peter O Jensen,Michael Givskov and Thomas Bjarnsholt
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    Volume : 12
  • 127. Human Genetic Data Banks: From Consent To Commercialization an Overview of Current Concerns and Conundrums

    Lori Luther and Trudo Lemmens
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    Volume : 12
  • 128. The Status of the Extracorporeal Embryo [Stem Cells]

    H. Nys and B. Hansen
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    Volume : 12
  • 129. Bioterrorism by Biotechnology: Implications For Clinical Medicine

    Gifty Immanuel
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    Volume : 12
  • 130. Human Papillomavirus-Mediated Transformation Of The Anogential Tract

    Renske D.M. Steenbergen, Jillian de Wilde, Saskia M. Wilting,Antoinette A.T.P.Brink, Peter J.F. Snijders and Chris J.L.M. Meijer
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    Volume : 12
  • 131. Social, Educational and Political Aspects of Biotechnology - An Overview and an Appraisal of Biotechnology in a Changing World

    Colin Ratledge
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    Volume : 13
  • 132. Some Social, Educational and Political Aspects of Biotechnology

    Ian Pownall
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    Volume : 13
  • 133. Public Policy Responses to Biotechnology

    Philipp Aerni,Peter Rieder
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    Volume : 13
  • 134. Inventions, Patents and Morality

    Darryl R. J. Macer
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    Volume : 13
  • 135. The Regulation of Genetically Modified Food

    S.J.Mayer
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  • 136. Biotechnology Education

    Gustavo Viniegra-González
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  • 137. Biotechnology in Rural Area

    Li Kangmin
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  • 138. Art Biotechnology and the Culture of Peace

    Edgar DaSilva
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  • 139. Why Genetic Modification Arouses Concerns: Social, Cultural And Political Impacts

    Richard Braun
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    Volume : 14
  • 140. Gender Relations in Local Plant Genetic Resource-Management and Conservation

    P. L. Howard-Borjas with W. Cuijpers
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  • 141. Biowarfare and Bioterrorism: The Dark Side of Biotechnology

    Edgar J. DaSilva
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  • 142. Social Factors in the Treatment and Reuse of Organic Wastes in Developing Countries

    Christine Furedy,Hanns-André Pitot
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  • 143. Potentials of Bioenergy from the Sago Industries in Malaysia

    K.B. Bujang
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  • 144. The Pacific Islands: A Natural Treasurehouse Of Bioresources and Island Biotechnology

    Edgar J. DaSilva,Murukesan V. Krishnapillai
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  • 145. The Role Of Microbial Resources Centers And UNESCO In The Development Of Biotechnology

    Horst W. Doelle,Faustino Sineriz
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    Volume : 15
  • 146. Biotechnological Activities Of The Mircens – History, Training And Research Until 2002

    Horst W. Doelle,Faustino Sineriz
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  • 147. Biological Nitrogen Fixation

    James Kahindi,Nancy Karanja,Mamadou Gueye
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  • 148. History And Achievements Of The Culture Collection And Patent Mircen Braunschweig[Germany]

    Dagmar Fritze
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  • 149. The Ex Situ Conservation Of Microorganisms: Aiming At A Certified Quality Management

    David Smith and Matthew J. Ryan,Erko Stackebrandt
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  • 150. Mircen-Bites Ljubljana: Cooperation For Research, Education And Development

    Bojana Boh
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  • 151. Microbiological Resources Centre (MIRCEN) at The Chinese University Of Hong Kong, Shatin, Hong Kong (1991-2003)

    Shu-Ting Chang,John A. Buswell
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    Volume : 15
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